John Rook - Process expert MSAT at Lonza - will be giving a lecture at Single-Use Event Basel 2026 about the introduction of Intensified Fed Batch (IFB) at large scale: A Hybrid Approach.
Lonza's new large-scale facility showcases intensified fed-batch (IFB) technology, delivering increased titers while maintaining product quality and lowering cost of goods (CoG). Using a hybrid model—stainless steel bioreactors integrated with single-use components—the process employs automated feeding and advanced PAT for real-time monitoring and control. This approach boosts volumetric productivity, enabling greater space-time yield. IFB at production scale combines productivity gains with operational flexibility, offering a validated, scalable platform for high-titer biologics manufacturing.
About the speaker
John Rook is a Process Expert in Manufacturing Science and Technology (MSAT) with over 20 years of experience in the biopharmaceutical industry. Specializing in upstream cell culture, technology transfer, and large-scale process optimization, John focuses on the seamless introduction, scale-up, and implementation of complex bioprocesses. Dedicated to advancing innovative bioprocess solutions while maintaining the highest standards of quality and compliance, he is passionate about supporting customers and promoting the developments in the biopharmaceutical manufacturing industry.
Lonza
Lonza is a pioneer and world leader in the CDMO industry, setting the pace with cutting-edge science, smart technology, and lean manufacturing. United by a common purpose, they turn their customers’ breakthrough innovations into viable therapies and manufacture the medicines of tomorrow.
Founded in Switzerland in 1897, the company is the first and original CDMO, and today they are more dynamic, agile and forward-focused than ever before. As one of the largest Western CDMOs, they bring together a global team of around 18,500 colleagues across five continents to deliver comprehensive, integrated solutions for their customers' complex needs.
Single-Use Event Basel 2026
Single-Use Event Basel 2026 is the ultimate networking event for professionals in bioprocessing, biotechnology and (bio)pharmaceutical manufacturing, with a focus on single use. Taking place on March 19, 2026, at Messe Basel, the event offers a full day of innovation, insights and interaction.
Meet exhibitors showcasing the latest solutions in single-use systems, bioprocessing technologies, and (bio)pharmaceutical production tools. From tubing systems and bioreactors to filtration units and smart monitoring solutions, the exhibition offers a hands-on look at what’s new and what’s next. Many companies will offer demos or product samples, and staff will be available to answer questions. The table-top setup ensures an open, accessible format where you can engage directly with technology suppliers and innovators throughout the day.
Read more about Single-Use Event Basel 2026